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The single-cell sequencing data presented in the study are deposited in the GEO repository, accession link Ethics statement The animal study was approved by We treated all mice according to the procedures approved by the experimental animal ethical committee of the Shandong Academy of Occupational Health and Occupational Medicine (NO.: SDZFY - EC - A- 202309)

Exp Mol Med 53 , 15801591 (2021)

Glycoprotein G-protein coupled receptors in disease: luteinizing hormone receptors and follicle stimulating hormone receptors

Because of these effects (skin tanning, weight reduction due to suppressed appetite and penile erections), Melanotan 2 became known as the Barbie drug. Lang et al first raised concerns about the potential adverse impact of illegally sold Melanotan 1 and 2 in an article published in the British Medical Journal [12]