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Patients should contact their GP or diabetes team if they experience: Severe, persistent abdominal pain (potential pancreatitis) Persistent vomiting leading to dehydration Signs of hypoglycaemia (if taking alongside insulin or sulphonylureas) Severe or persistent constipation or abdominal distension Right upper quadrant pain, fever or jaundice (potential gallbladder problems) Sudden visual changes (especially in those with diabetic retinopathy) Allergic reactions or injection site problems Weight loss typically becomes noticeable within the first few weeks to months, though the rate varies considerably between individuals
Dhillon S, Keam SJ
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In line with this study, analysis of the PCa in vitro models demonstrated that patient-derived cell cultures and established cell lines can be radiosensitized by GLS inhibition with CB-839 or MYC inhibition with 10058-F4
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