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Oral glutathione has very limited bioavailability and cannot reliably achieve therapeutic plasma concentrations

10.1038/srep38887 81 LeeJ.SugiyamaT.LiuY.WangJ.GuX.LeiJ.et al (2013)

Advantages over traditional liposomes Traditional liposomal systems usually come in liquid form, which involves certain limitations in terms of stability, need for refrigeration, and use of additives or preservatives to maintain integrity

Accordingly, early deficiency in systemic glutathione is likely to contribute to the progression of the cardiac disease