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Possible Side Effects Observed in Research Settings Because Tirzepatide interacts with GLP-1 and GIP receptor pathways involved in appetite regulation, glucose signaling, digestion, and metabolic function, observed responses in research settings are commonly gastrointestinal and metabolic in nature

This combination makes staying hydrated absolutely critical

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Within 12 months, the average dosage increased to 80 mcg/kg SC twice daily (range = 60 mcg/kg to 120 mcg/kg SC twice daily)