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I am hopeful that with all the emerging research, we will again start to understand the importance of living, probiotic-rich foods and bacterial exposure from other sources and address this problem on a wider level as well

Our experience suggests that while a systemic dose will eventually reach the ankle, a localized dose may create a much higher concentration gradient in the target tissue for a more potent and immediate effect

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Differences between groups were compared via two-tailed unpaired t tests for two groups, one-way analysis of variance (ANOVA) followed by Dunnetts multiple comparison test for multiple groups, or two-way repeated-measures ANOVA followed by the Bonferroni multiple comparison test for multiple groups and time courses