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This combination of insulin resistance and -cell failure further amplifies hyperglycemia, creating a vicious cycle of metabolic dysfunction and ROS production that fuels widespread cellular injury and inflammation across multiple organ systems

Sedating antihistamines should be avoided, particularly in older adults or those who must avoid impairment

The tripeptide modulates over 4,000 human genes (31.2% of the genome) and plasma levels decline from approximately 200 ng/mL at age 20 to less than half by age 60 (Pickart & Margolina, 2018)

Plant Foods, Antioxidant Biomarkers, and the Risk of Cardiovascular Disease, Cancer, and Mortality: A Review of the Evidence