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Frias JP, Davies MJ, Rosenstock J, Perez Manghi FC, Fernandez Lando L, Bergman BK, Liu B, Cui X, Brown K, Investigators, S.-

This substance was first approved as an addition to diet and exercise plans for patients with type 2 diabetes in 2010 and was mainly sold under the brand name Victoza

It is not as effective for subcutaneous belly fat, which sits above the muscle layer and has a different hormonal and metabolic profile

Moreover, evidence from an increasing number of research studies suggests that, in addition to its effects on neuroendocrine and metabolic functions, GHSR contributes to the regulation of the mesocorticolimbic pathway and influences diverse reward-related behaviors in response to various stimuli through both ligand-dependent and -independent mechanisms (49)