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GLP-1 receptor activation enhances mitochondrial biogenesis through modulation of PGC-1, thereby improving oxidative phosphorylation, ATP production, and calcium buffering capacity [54,55]

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El GLP-1 forma parte de la familia de los pptidos derivados del proglucagn, y acta a travs de su receptor especfico, el GLP-1R, el cual se encuentra ampliamente distribuido en pncreas, cerebro, sistema digestivo y otros tejidos

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