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The quantity required to decompose 1 mol of H 2 O 2 per minute determines unit activity of enzyme

J Craniomaxillofac Surg

It can only be hypothesized that a reduced, but not abolished, residual activity is sufficient to impair glutathione recycling but not to attenuate ROS production via uncoupled NOS and NADH/NADPH oxidase that utilize NADPH to generate superoxide [94]

Due to this added complexity, orthogonal methods are required to characterize the critical quality attributes. This popularity has come with significant caveats