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Preparation and Storage Supplied as a lyophilized (freeze-dried) powder in a sealed research vial Reconstitute with bacteriostatic water before use in laboratory settings Store refrigerated at 28C

The article names patients with kidney disease, liver impairment, and anyone taking immunosuppressants

[PubMed] [Google Scholar] 14.Brasaemle DL, Dolios G, Shapiro L, Wang R

This leads to the cleavage and translocation of AIF from the mitochondrial intermembrane space to the nucleus, phosphorylation of the histone H2A family member H2AX, mitochondrial release of the death-inducing protein Smac/direct IAP-binding protein with low PI (DIABLO), and inhibition of the anti-apoptotic protein X-linked inhibitor of apoptosis (XIAP)