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Insurance coverage, manufacturer self-pay programs (Lilly Direct, NovoCare), Medicare rules, and cash-pay compounded telehealth all sit on top of the same molecules and produce wildly different out-of-pocket totals

In Table 2, we evaluated the number of first-time NAION events, person-years at risk, incidence rates, and we performed a crude and a multivariable Cox proportional hazard regression adjusted for sex, age, marital status, duration of diabetes, hemoglobin A1c, estimated glomerular filtration rate, history of cardiovascular disease, use of insulin, use of cholesterol lowering medicine, and use of blood pressure lowering medicine

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Potential Cardiovascular Benefits: Some GLP-1 agonists, such as semaglutide, have shown to reduce the risk of major cardiovascular events (e.g., heart attacks, strokes), particularly in patients with type 2 diabetes