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Do not stop or restart medications on your own

The 2.5 mg starting dose is not meant to be therapeutic on its own

17 : 16751687 Fulda S, Meyer E, Friesen C, Susin SA, Kroemer E and Debatin KM (2001) Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

Jack Khattar, president & CEO of Supernus, said the company remain[s] committed to bringing SPN-830 to the market and will work with the FDA to address the issues identified in the CRL and resubmit the NDA