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Since its first description in the peer-reviewed literature by Neelakantan et al

These gels were readily homogenized, washed, and used to purify soluble GST proteins

Theoretically those subject carriers of CYP2D6 functional alleles (including those carriers of duplications) and with a low COMT activity should be the most efficient in generating metabolic neurotoxic species and, consequently, the most vulnerable to neurotoxicity

Influence of a specialized Trigonella foenum-graecum seed extract (Libifem), on testosterone, estradiol and sexual function in healthy menstruating women, a randomised placebo controlled study