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In addition, AML cells overexpressing WT BCAT 1 had lower ROS, and the number of bone marrow markers (CD11b, CD14, CD68, and CD36) that marked cell differentiation on the cell surface was lower, suggesting the involvement of the BCAT 1 CXXC motif in ROS buffering and cell development in AML cells

A randomized controlled trial indicated that curcumin supplementation resulted in significant improvements in liver enzyme levels and histological features of liver steatosis among patients with NAFLD, underscoring its therapeutic potential

While not FDA-approved specifically for liver disease, growing data support their off-label use in MASLD under physician guidance

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease