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Step 4: Then it reduces the enzyme tyrosinase, essential for melanin production

The presence of oxidative stress markers like lipid peroxidation, neutrophil reverse trans-endothelial migration (rTEM) and high neutrophil to lymphocyte ratio in patients with COVID-19, facilitates identification of high-risk individuals early in the course of the disease preventing their sudden deterioration (Laforge et al., 2020)

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In adults, it is more likely to be found on the backs of the upper arms, the thighs, and the buttocks