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I did notice the libido increase, especially on the 40 units, some at the 20 units, and no extra libido at 10 units

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Sleep problems at different tirzepatide dose levels Sleep disruption risk varies by dose, primarily because higher doses produce more aggressive appetite suppression and gastric slowing

Reduced gastrointestinal motility and altered drug absorption may require dose adjustments of medications including warfarin, direct oral anticoagulants, opioids, and antiepileptic agents