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The formation of phagophore (also called isolation membrane or autophagosome precursor) occurs primarily at the ER which ultimately elongates and encloses forming the autophagosome structure (Ravikumar et al., 2009)

The key is to understand each component's role before combining them

For facilities that received more than 200 completed surveys, the facility would have the option to randomly sample from these surveys for reporting the measure results

That's a remarkable headline number, and it's driven significant interest despite the limited human data available