This occurs in peripheral circulation and can promote symptoms such as postural orthostatic tachycardia syndrome (PoTS), PEM, fatigue, endothelial cell dysfunction, platelet hyperactivation, mast cell activation, and connective tissue disorders
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Sensory nerve damage produces the symptoms most people associate with neuropathy: numbness, tingling, burning pain, pins-and-needles sensations, and hypersensitivity to touch
However, for any study involving oral administration, long-term protocols, or situations where temperature control might be inconsistent, the extra investment in the arginate salt is, in our professional opinion, well worth it