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9.1 Drug delivery and therapy The intracellular redox potential of the glutathione/glutathione disulfide (GSH/GSSG) couple in mammalian cells typically ranges between 2260 mV and 200 mV, which is significantly more negative than the extracellular environment (approximately 140 mV) Fig

Lieberman HR, Wurtman RJ, Emde GG, Roberts C, Coviella IL (1987) The effects of low doses of caffeine on human performance and mood