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Loss of Muscle Mass Rapid weight loss without enough protein or resistance training can lead to muscle loss

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Consult your doctor if you have: Pancreatitis or a history of inflammation in the pancreas

[See Clinical Pharmacology.] Concomitant Use with a Sulfonylurea When Januvia is used in combination with a sulfonylurea, a lower dose of sulfonylurea may be required to reduce the risk of hypoglycemia