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The expression level of Nogo-B correlated with tumor vessel density in hepatocellular carcinoma and anti-Nogo-B antibody inhibited tumor growth in vivo via suppressing tumor angiogenesis [222]

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This estimate does not include rebates, which Medicares actuaries estimated to be 31.5% overall in 2022 but could be as high as 69% for Ozempic, according to one estimate