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8 , e12268 (2022)

Our Score: 9.2/10 | Trustpilot: 4.0 (435+ reviews) Overview Shed (also known as ShedRx) is a Phoenix-based telehealth platform offering compounded semaglutide and tirzepatide in more formats than almost any other provider on our list: weekly injections, daily sublingual drops, and daily dissolvable lozenges

When you lose too much weight too quickly, it can accelerate muscle loss and increase the risk of falls, injuries, and even long-term disability

5 Randomized data suggest that intermittent energy restriction achieves similar HbA1c reductions to continuous energy restriction, with no clear between-group differences in GLP-1 concentrations, so any specific GLP-1 benefit of IF remains uncertain