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Summary: Retatrutide fatigue is most pronounced during the dose escalation phase and commonly begins to improve once the dose stabilises, though the precise duration varies between individuals

Night eating syndrome in patients with obesity and binge eating disorder: a systematic review

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In August 2025, Novo Nordisk announced that the FDA has approved WEGOVY as the first GLP-1 receptor agonist for adults with Metabolic Dysfunction-associated Steatohepatitis (MASH) who have moderate to advanced fibrosis, excluding cirrhosis, in combination with diet and exercise