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The absence of IGF-1 elevation carries important safety implications

Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

A multi-epitope/CXCL11 prime/pull coronavirus mucosal vaccine boosts the frequency and the function of lung-resident CD4+ and CD8+ memory T cells and protects against COVID-19-like symptoms and death caused by SARS-CoV-2 infection