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In the absence of any significant muscle or cardiac manifestations, the acute hepatic presentation of CPT1 deficiency cannot be distinguished on a clinical basis from other defects of long-chain fatty acid oxidation and conditions that present as a Reye-like illness

Antigen retrieval was achieved by heating the sections in 10 mM sodium citrate buffer (pH 6.0) at 100 C for 20 min

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Using quantitative measurements of 54 metabolites and their ratios in a carefully selected cohort of 499 autistic and 209 typically developing controls that are ages 1848 months, we identified 153 autism-associated biomarkers