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Brain cholesterol metabolism and its defects: linkage to neurodegenerative diseases and synaptic dysfunction

If weight loss is your goal, GLP-1 receptor agonists like semaglutide are evidence-based options that also improve metabolic health

Studies addressing the effects of ES as well as nutritional interventions in both males and females were included, however the literature to date mostly fails to test whether the efficacy of the nutritional intervention is sex-specific

The blood sugar-raising effect of steroids can blunt the glucose-lowering benefit of semaglutide, requiring higher semaglutide doses or more frequent monitoring to achieve therapeutic targets