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Because of that, plants developed complexed ROS control system based on enzymes (like glutathione reductase-GR, glutathione S-transferase-GST, glutathione peroxidase-GPX) and scavenging non-enzymatic hydrophilic molecules like ascorbate (AsA) and glutathione (GSH) (Yang et al., 2019

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A randomized clinical trial in 2019 also showed increase in pregnancy rates in women with PCOS undergoing artificial insemination who took 3mg melatonin per night from the 3rd day of menstruation to the day of gonadotropin injections started