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PubMed, NCBI

No serious adverse events were attributed to AOD-9604 across the entire clinical trial program involving over 900 participants

Gut microbiota: primary producers of trimethylamine Gut microbiota, particularly Firmicutes and Proteobacteria , are key mediators of TMA production through distinct enzymatic pathways (51, 52)

Clinicians emphasize the importance of monitoring vitamin and mineral levels to avoid toxicity, especially with high doses of certain nutrients such as vitamin A, folic acid, and zinc