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39 The study of these clinical properties in small molecule GLP-1RAs is an undergoing area of study

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In AD mouse models, pathophysiological changes, such as anti-apoptotic effects, reduced A deposition and phosphorylated hippocampal tau, protection from synapse loss, reduced inflammatory and oxidative stress response in the cortex and hippocampus, and increased BDNF have been observed [119,120,121]

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