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S-glutathionylation can regulate a variety of intracellular physiological or biochemical processes such as oxidative stress, cellular metabolism, transcription and translation, protein folding, free radical scavenging, cell motility, and apoptosis by modulating protein function or activity

There is a plausible rationale for zinc as supplementation to improve insulin resistance, lipid metabolism and hyperandrogenism in PCOS animals and patients ( Zinc is necessary for many physiological functions including insulin production, storage, and action

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Glutathione deficiency is commonly associated with Parkinsons disease, alcoholism, Alzheimers disease and chronic fatigue syndrome