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[243] [244] In contrast to human studies, adult female rats exhibit markedly greater dopamine release in the nucleus accumbens and more pronounced behavioral effects from amphetamine administration relative to males, effects that may be modulated by fluctuating estradiol levels across the estrous cycle or more broadly by adult gonadal hormones

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Alogliptin protects against cyclophosphamide induced lung toxicity by reducing oxidation, inflammation and fibrosis, making it a promising pharmacological treatment for reducing lung toxicity [75]