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Randomized controlled trials demonstrate that periconceptional supplementation with folic acid (i.e., beginning one month before conception until the end of the first trimester) dramatically reduces the occurrence of NTDs

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10.1016/j.molliq.2024.125446 21 Bautista-SnchezD.Arriaga-CanonC.Pedroza-TorresA.De La Rosa-VelzquezI