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FUNDING: This study was supported by the Key Project of Natural Science Foundation of Shandong Province (ZR2021ZD33)

Laser Skin Whitening Treatments Mode of Action: Utilizes laser technology to target melanin and reduce pigmentation

This approach allows earlier treatment initiation and avoids the risks and delays associated with invasive diagnostic procedures

Data analysis Raw files were searched through Proteome Discoverer v.2.3 (Thermo Scientific) and spectra were queried against the human proteome (database downloaded from uniprot.org on 02/12/2019, containing 73662 sequences) using Sequest HT with a 1 % false discovery rate (FDR) applied