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In real-world practice, those discontinuation rates may be even higher. Andrade said the medication could be helpful for people with severe obesity, who may still have trouble losing weight on the existing GLP-1 medications, although shed like to see more data on the side effects

Patients on Tirzepatide 15 mg weekly lost an average of 20.9% or 48.6 lb of their body weight after 72 weeks in the Zepbound Study 1 (NCT04184622) compared to placebo patients who lost an average of 3.1% or 7.2 lb

Novo Nordisk has prioritized the expansion of semaglutide medications, including Ozempic, in response to the soar in demand and to stabilize the supply chain for those whose treatment depends on it