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Some hypothetical explanations for the weaker anti-obesity response for both GLP-1 RAs in people with diabetes include the background medications that promote weight gain, the fear of hypoglycaemia inherently related to the treatment of diabetes, a decrease in glycosuria and subsequently less weight loss in diabetics, an altered microbiota in patients with obesity and diabetes and a genetic background that predispose to weight gain in patients with diabetes
For many patients exploring weight loss medication combinations , phentermine serves as a first-line option because of its low cost and decades of clinical history
It is a valuable aid for weight loss and physical performance so can help support you with your weight management or physique goals
[Biochimie, 2014, vol
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