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Medications that reduce stomach acid, such as proton pump inhibitors (PPIs) and H2-receptor antagonists, can impair the absorption of dietary B12, making high-dose liquid supplementation even more critical for patients on these drugs

Because of this, lots of people have mild to moderate vitamin B12 deficiencies due to unbalanced diets or other factors

These are usually mild and temporary

Laboratory studies using 5-amino-1MQ in aged animal models have revealed that NNMT inhibition modulates many age-associated metabolic parameters, including alterations in muscle tissue metabolism and cellular stress response pathways