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Patients with type 2 diabetes, HTG (200 to 499 mg/dl), and HDL-C ( 40 mg/dl) or lower were randomized to receive pemafibrate (0.2 mg tablets twice daily) or placebo

However, these do have to be prescribed and administered by a healthcare professional, and are more likely to be given to people who have lifelong conditions affecting their ability to absorb B12 or who are at higher risk of consistent deficiency

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Ali Rezaie, Medical Director of Gastroenterology Motility at Cedars-Sinai Medical Center, emphasized the need for context, noting that while the relative risk increases by 33%, the absolute risk remains low at 0.2%