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Description

Sever M, Klicek R, Radic B, et al

142 The sulphur-containing residues, methionine and cysteine, account for 40%80% of the total antioxidant activity of HSA

The ratio of areas (AUC PO /AUC IV ) reveals oral bioavailability, since AUC is proportional to the amount of drug that was present within the systemic circulation

The DAC version (Drug Affinity Complex) binds to albumin in the blood, which dramatically extends its half-life