is semaglutide a sglt2 inhibitor once weekly as add-on to SGLT-2 therapy in type 2 diabetes (SUSTAIN 9): randomised, placebo-controlled trial GLP-1 Receptor Agonist Therapy With

Wang L, Kounatidis I, Ligoxygakis P

Summary: There is no official contraindication preventing concurrent use of L-carnitine and Mounjaro, but no robust evidence demonstrates additional benefits from this combination

Unlike traditional treatments that target only CSF production, GLP-1 agonists may work through two pathways: Weight loss - a major long-term treatment for IIH Possible CSF pressure effects - GLP-1 receptors on the choroid plexus (where CSF is made) may reduce fluid secretion independent of weight loss The IIH Pressure Trial ( Brain , 2023) found that exenatide lowered intracranial pressure within hours of the first dose

Nevertheless, the potential involvement of other classical phagocytic cues, such as oxidized phosphatidylserines (oxPSs), warrants further rigorous investigation