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Since leptin reduces sweet taste sensitivity, diminished leptin signaling in the CNS may contribute to the reduced sweet taste sensitivity observed in individuals with obesity (127)

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2.7 Single-gene Gene Set Enrichment Analysis and Gene Set Variation Analysis analysis of key genes To explore the potential regulatory mechanisms of key genes in RA, GSEA and GSVA were performed to evaluate the association between key genes and HALLMARK pathways

PubMed CrossRef Richards JR, Dorand MF, Royal K, et al