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The hemoglobin fractionation assay confirmed that E64d-treated parasites have significantly decreased heme and hemozoin levels, while undigested hemoglobin levels were elevated following treatment (Supp Fig 2A)

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Composition of Liquid L-carnitine with synephrine Per 30 ml: Water, Thickener: glycerin, L-Carnitine base (1500 mg), Dry orange extract (Citrus aurantium L., fruit standardized to 6% Synephrine) (100 mg), Preservative: potassium sorbate, Lemon powder flavor, Acidity regulator: citric acid