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The Science 5-Amino-1MQ is a small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that influences cellular energy metabolism by modulating the methylation of nicotinamidea key component in NAD+ synthesis and cellular energy production
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The molecule has been studied in animal models of adipose-tissue metabolism, with published preclinical work examining its effects on NAD+ pool dynamics and on the methyl-donor balance NNMT regulates
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