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These dogs were mostly neutered and were being fed a variety of quality commercial diets

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In the literature, GSH has been encapsulated into various galenic forms for oral administration: liposomes [116], water-in-oil microemulsions [117], pellets of montmorillonite and glutathione [118], polymeric NPs and microparticles prepared with natural or synthetic polymers [119,120,121], hydrogels [122], and mucoadhesive films for sublingual delivery [123], as well as orobuccal tablets in combination with l-cystine, vitamin C and selenium [124]

Another theory suggests elevated estrogen levels that occur as men age may increase cellular growth activity leading to BPH