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Primary outcome measures clinical remission at week 48 based on modified Mayo subscores, with secondary endpoints including endoscopic improvement, corticosteroid-free remission, and comprehensive safety assessments including AEs, laboratory parameters, and immunogenicity through week 48
These findings indicate that the homeostasis of carnitine and TMAO regulated by the kidney are considerably different
The FDA has approved Wegovy, Zepbound, and Saxenda to help with weight loss
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