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We included peer-reviewed articles written in English that investigated the impact of GLP-1 RAs on bone health, bone metabolism, or bone remodeling in human subjects or relevant animal models

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While some users report enhanced local effects, the evidence for superiority over subcutaneous administration remains unclear, and complications including nerve irritation present greater concern

Skipping ahead to higher doses to lose weight faster is one of the strongest predictors of severe muscle loss in clinical observation