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Razzaque MS, Wimalawansa SJ (2025) Minerals and human health: From deficiency to toxicity

This multi-level regulation keeps glutamate within its tight physiologic range. Excess causes excitotoxic neuronal death (as in stroke), while deficiency impairs learning and memory

Participants in the semaglutide group will follow a semaglutide dose-escalation regimen (the maintenance dose of 0.51.0 mg will be reached after 4 weeks of 0.25 mg semaglutide administration once weekly)

These ROS can trigger and amplify inflammatory responses, creating a cycle of tissue damage and immune dysfunction