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10.1038/ng1089 100 JagetiaG

Hemochromatosis Hemochromatosis is a disorder in which the body stores too much iron

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Glutathione peroxidase (GPX) role in oxidative stress and its interaction with superoxide dismutase (SOD) The SOD gene locus resides on chromosome 21 and as a consequence of gene dosage excess, SOD activity has been shown to be increased by about 50% in all tissues of patients with Down syndrome (Brooksbank & Balzas, 1983