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Semaglutide's pharmacological action centres on mimicking the effects of natural GLP-1, a hormone released by the intestine in response to food intake

Effect of semaglutide on bone mineral density (BMD) in ovariectomized rats The examination of bone performed by DEXA showed that ovariectomy reduced BMD in the spine, femur, and tibia by 29.2%, 33.5%, and 24.2%, respectively, when compared to the control group