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A personalized approach considers: Your BMI and weight loss goals Blood sugar response Side effects (especially nausea and GI symptoms) Coexisting health conditions like PCOS or hypothyroidism Whether you're using it for diabetes, obesity, or both Doctors usually start you on the lowest dose, then increase it every few weeks if tolerated

The oral glutathione supplement was slightly beneficial for skin lightening in particular subgroups, but the results were not statistically significant

Beyond validated scores, a few laboratory values have emerged as potential markers of severity