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This retrograde signaling mechanismmitochondria communicating upstream to the nucleusis what Brnice Benayoun, a faculty member at USC Leonard Davis and co-author on the Reynolds et al

developed gold-loaded metalorganic frameworks (Au-MOFs) in which GSHs SH and COOH groups promote strong interactions between gold nanoparticles and the MOFs amine functionalities, enhancing fluorescence by restricting internal molecular motion [92]